Limbs mineralization problems and you can supplement D insufficiency: histomorphometric study out-of iliac crest limbs biopsies and circulating 25-hydroxyvitamin D during the 675 clients. J Bones Miner Res 2010; 25: 305–312.
Zhou Y, Zhao LJ, Xu X mais aussi al. DNA methylation degrees of CYP2R1 and CYP24A1 anticipate supplement D impulse type. J Steroid Biochem Mol Biol 2014; 144: 207–214.
Ralston SH, Binkley N, Boonen S mais aussi al. Randomized trial out of alendronate and additionally supplement D3 in the place of standard worry during the osteoporotic postmenopausal ladies having supplement D deficiency. Calcif Tissues Int 2011; 88: 485–494.
Weber K, Kaschig C, Erben RG . step 1 Leader-hydroxyvitamin D2 and you may step one alpha-hydroxyvitamin D3 keeps anabolic effects towards the cortical bone, but result in intracortical remodeling during the dangerous dosages into the ovariectomized rats. Bones 2004; 35: 704–710.
Li M, Healy DR, Simmons HA ainsi que al. Alfacalcidol regulates cancellous bones during the ovariectomized rats. J Musculoskelet Neuronal Work together 2003; 3: 39–46.
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Cures which have elage, and you may collagen crosslinks inside the primate bone
Orimo H, Shiraki M, Hayashi Y et al. Aftereffects of 1 alpha-hydroxyvitamin D3 to the lumbar bone mineral thickness and you can spine splits in clients which have postmenopausal weakening of bones. Calcif Muscle Int 1994; 54: 370–376.
Shikari Kushida Yards, Yamazaki K, Nagai K ainsi que al. H. Ramifications of dos years’ remedy for weakening of bones which have 1 alpha-hydroxy vitamin D3 on bone mineral thickness and chance out-of break: a great placebo-managed, double-blind possible study. Endocr J 1996; 43: 211–220.
Nuti Roentgen, Bianchi G, Brandi ML ainsi que al. Quality off alfacalcidol compared to supplement D plus calcium supplements during the lumbar bone mineral thickness from inside the postmenopausal weakening of bones. Rheumatol Int 2006; 26: 445–453.
Kubodera N, Tsuji Letter, Uchiyama Y mais aussi al. Another type of active vitamin D analogue, ED-71, grounds escalation in bone bulk with preferential outcomes into bone within the osteoporotic customers. J Cell Biochem 2003; 88: 286–289.
Abe M, Tsuji N, Takahashi F mais aussi al. Article on the brand new medical pharmacokinetics from elin D3 derivative. Jpn Pharmacol Ther 2011; 39: 261–274.
Ritter CS, Brownish AJ . Suppression away from PTH of the nutritional D analog eldecalcitol is modulated by the the high attraction to your serum vitamin D-joining proteins and resistance to kcalorie burning. J Cellphone Biochem 2011; 112: 1348–1352.
Kondo S, Takano T, Ono Y ainsi que al. Eldecalcitol decrease osteoporotic splits because of the book systems. J Steroid Biochem Mol Biol 2015; 148: 232–238.
Harada S, Mizoguchi T, Kobayashi Y ainsi que al. Day-after-day administration off elin D analogue, develops bones nutrient occurrence because of the inhibiting RANKL term into the mouse trabecular bone. J Limbs Miner Res 2012; 27: 461–473.
Hayashi Y, Fujita T, Inoue T
Matsumoto T, Ito M, Hayashi Y ainsi que al. A different sort of productive supplement D3 analogue, eldecalcitol, suppress the risk of osteoporotic cracks–a randomized, active comparator, double-blind investigation. Limbs 2011; 49: 605–612.
Matsumoto T, Takano T, Saito H mais aussi al. Supplement D analogs and you can bones: preclinical and you will clinical studies that have este; 3: 513.
Sakai A good, Ito Meters, Tomomitsu T et al. Efficacy out of shared medication with alendronate (ALN) and you can elin D analog, to that particular of concomitant ALN, nutritional D and calcium cures into the Japanese customers having pri; 26: 1193–1202.
Plum La, Fitzpatrick Los angeles, Ma X ainsi que al. 2MD, a new anabolic representative for weakening of bones therapy. Osteoporos Int 2006; 17: 704–715.
Ke HZ, Qi H, Crawford DT et al. A new vitamin D analog, 2MD, restores trabecular and you will cortical bone bulk and power inside the ovariectomized mice that have created osteopenia. J Limbs Miner Res 2005; 20: 1742–1755.
DeLuca HF, Bedale W, Binkley Letter et al. New nutritional D analogue 2MD develops bone turnover yet not BMD during the postmenopausal females having osteopenia: results of a 1-seasons stage dos double-blind, placebo-regulated, randomized clinical trial. J Bones Miner Res 2011; 26: 538–545.